IMP_dehydrogenase

IMP dehydrogenase

IMP (inosine monophosphate) dehydrogenase 1

Identifiers

Symbol IMPDH1

Alt. Symbols RP10

Entrez 3614

HUGO 6052

OMIM 146690

RefSeq NM_000883

UniProt P20839

Other data

EC number 1.1.1.205

Locus Chr. 7 q31.3-q32

IMP (inosine monophosphate) dehydrogenase 2

Identifiers

Symbol IMPDH2

Entrez 3615

HUGO 6053

OMIM 146691

RefSeq NM_000884

UniProt P12268

Other data

EC number 1.1.1.205

Locus Chr. 3 p21.2

IMP dehydrogenase is an enzyme which converts inosine monophosphate to xanthosine monophosphate.

References

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v • d • e Oxidoreductases: alcohol oxidoreductases (EC 1.1)

1.1.1 NAD/NADP acceptor	Carbohydrate dehydrogenases - Alcohol dehydrogenase - Glycerol-3-phosphate dehydrogenase - L-xylulose reductase - Aldose reductase - Lactate dehydrogenase - 3-Hydroxyacyl CoA dehydrogenase - Malate dehydrogenase - Isocitrate dehydrogenase - Phosphogluconate dehydrogenase - Glucose-6-phosphate dehydrogenase - HMG-CoA reductase - Β-Ketoacyl ACP reductase Hydroxysteroid dehydrogenase: 11 Beta (HSD11B1, HSD11B2) - 3 Beta (3-beta-HSD) - 17 Beta Carnitine dehydrogenase - Beta-hydroxybutyryl-CoA dehydrogenase - IMP dehydrogenase - DXP reductoisomerase - L-threonine dehydrogenase

1.1.2 cytochrome acceptor	Mannitol dehydrogenase (cytochrome) - D-lactate dehydrogenase (cytochrome) - D-lactate dehydrogenase (cytochrome c-553)

1.1.3 oxygen acceptor	Glucose oxidase - L-gulonolactone oxidase - Xanthine oxidase

1.1.4 disulfide as acceptor	Vitamin K epoxide reductase - Vitamin-K-epoxide reductase (warfarin-insensitive)

1.1.5 quinone/similar acceptor	Quinoprotein glucose dehydrogenase

1.1.99 other acceptors	Choline dehydrogenase

v • d • e

Anabolism	R5P->IMP: Ribose-phosphate diphosphokinase - Amidophosphoribosyltransferase - Phosphoribosylglycinamide formyltransferase - AIR synthetase (FGAM cyclase) - Phosphoribosylaminoimidazole carboxylase - Phosphoribosylaminoimidazolesuccinocarboxamide synthase - IMP synthase IMP->AMP: Adenylosuccinate synthase - Adenylosuccinate lyase - reverse (AMP deaminase) IMP->GMP: IMP dehydrogenase - GMP synthase - reverse (GMP reductase)

Nucleotide salvage	Hypoxanthine-guanine phosphoribosyltransferase - Adenine phosphoribosyltransferase

Catabolism	Adenosine deaminase - Purine nucleoside phosphorylase - Guanine deaminase - Xanthine oxidase - Urate oxidase

Anabolism	CAD (Carbamoyl phosphate synthase II, Aspartate carbamoyltransferase, Dihydroorotase) Dihydroorotate dehydrogenase - Orotidine 5'-phosphate decarboxylase/Uridine monophosphate synthetase CTP synthase

Catabolism	Dihydropyrimidine dehydrogenase - Dihydropyrimidinase/DPYS - Beta-ureidopropionase/UPB1

see also disorders, intermediates

IMP (inosine monophosphate) dehydrogenase 1
Identifiers
Symbol	IMPDH1
Alt. Symbols	RP10
Entrez	3614
HUGO	6052
OMIM	146690
RefSeq	NM_000883
UniProt	P20839
Other data
EC number	1.1.1.205
Locus	Chr. 7 q31.3-q32